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PARA ANISIC ACID

CAS NO. 100-09-4 | 4-Methoxy Benzoic Acid

General Information

Chemical Structure

Para Anisic Acid Chemical Structure

Basic Details

CAS Number: 100-09-4
Molecular Formula: C8H8O3
Molecular Weight: 152.15 g/mol
Appearance: White to almost white powder to crystal

Physical Properties

Density: 1.385 g/cm³
Boiling Point: 275 - 280 °C
Melting Point: 182 - 185 °C
Flash Point: 185 °C
Solubility: Soluble in alcohol, ether, chloroform; slightly soluble in hot water

Applications & Grade

Para Anisic Acid is a valuable intermediate in the pharmaceutical industry, serving as a key building block for the synthesis of various active pharmaceutical ingredients (APIs).

  • Used in the synthesis of Amiodarone HCl (an antiarrhythmic drug).
  • Key intermediate for Raloxifene HCl (a selective estrogen receptor modulator).
  • Precursor for Vanillic acid.
  • Intermediate in the production of Nootropics like Aniracetam.

Due to its antiseptic and preservative properties, Para Anisic Acid is increasingly used in the personal care industry as a safer alternative to traditional preservatives.

  • Commonly found in personal care products.
  • Used as a preservative in creams and lotions to prevent microbial growth.
  • Can be found in formulations for diapers.

Para Anisic Acid is found naturally in anise and possesses a faint, sweet, and slightly hawthorn-like aroma. It is used as a flavoring agent in foods and as a fragrance ingredient in perfumes.

  • Used as a flavoring agent in various food products, including cocoa, cream vanilla, licorice, berry, and tropical fruit essences.
  • Functions as a fragrance ingredient in perfume compositions.
  • Can act as an odor-masking agent to neutralize undesirable smells.
  • Plays a role as a fixative in certain essence formulations, helping to prolong the scent.

Beyond its primary uses, Para Anisic Acid has diverse applications in various industrial sectors.

  • Used in photographic chemicals.
  • Functions as an insect repellent and ovicide (substance that kills insect eggs).
  • Serves as an intermediate in the dye industry.
  • Employed as a laboratory reagent for various chemical reactions and analyses.

Our Para Anisic Acid is available in specific grades to meet the stringent requirements of different industries.

  • **Pharma Grade:** Meets high purity standards suitable for pharmaceutical synthesis and drug manufacturing.
  • **Cosmetics Grade:** Formulated and tested to comply with safety and quality standards for use in personal care and cosmetic products.

Product Specifications

Property Specification
Description White Odourless Powder
Solubility Soluble in Alcohol, Acetone and Dichloro Ethane
Identification Melting range, °C 182 °C - 184 °C
Chloride Not More Than 500 PPM
Sulphate Not More Than 1000 PPM
Moisture Content, w/w Not More Than 0.5 %
Sulphated Ash Not More Than 0.1 %
Assay on dried basis, w/w 99.0 % - 100.5 %

Certificate of Analysis

Certificate of Analysis
Product Name: Para Anisic Acid
(CAS No. 100-09-4)
Batch No.: PAA/B-19/17-18
Quantity: 1000 kg
Pack Size: 40 x 25 kg
Mfg Date: July-2017
Date of Analysis: 27/07/2017
Expiry Date: June-2020
A.R. No.: FGT/07/17/233

Description

Specification: White Odourless Powder

Results: White Odourless Powder

Solubility

Specification: Soluble in Alcohol, Acetone and Dichloro Ethane

Results: Complies

Identification Melting range, °C

Specification: 182 °C - 184 °C

Results: 184.0°C

Chloride

Specification: Not More Than 500 PPM

Results: Complies

Sulphate

Specification: Not More Than 1000 PPM

Results: Complies

Moisture Content, w/w

Specification: Not More Than 0.5 %

Results: 0.18%

Sulphated Ash

Specification: Not More Than 0.1 %

Results: 0.069 %

Assay on dried basis, w/w

Specification: 99.0 % - 100.5 %

Results: 99.50 %

P-Methoxy Benzoic Acid (HPLC)

Specification: >99.5%

Results: 99.87%

P-Hydroxy Benzoic Acid (HPLC)

Specification: <0>

Results: 0.042%

o-Anisic Acid (HPLC)

Specification: <0>

Results: Not Detected

m-Anisic Acid (HPLC)

Specification: <0>

Results: Not Detected

Additional test - Black particle test

Specification: Passes the test

Results: Complies

Conclusion: Material complies with above mentioned specifications
July 27, 2017
Analysed By:
V.M.Patel (QC Chemist)
Checked By:
N.M. Shah (QC Manager)
Approved By:
V.Prasad (Technical Head)

Spectroscopic Analysis

HPLC Chromatogram Coming Soon!

We are currently preparing the interactive HPLC data for Para Anisic Acid.

Please check back later for detailed chromatographic analysis.

Packaging, Handling & Storage

Packaging

  • Typically supplied in sealed, moisture-proof containers such as fiber drums with inner PE liners, or bags.
  • Available in various sizes (e.g., 25kg, 50kg, 500kg, 1000kg) to meet specific customer requirements.
  • Containers are designed to protect the product from moisture and contamination.

Handling

  • Handle in a well-ventilated area or under local exhaust ventilation to prevent dust inhalation.
  • Avoid direct contact with skin, eyes, and clothing.
  • Wear appropriate personal protective equipment (PPE): chemical-resistant gloves, safety goggles/face shield, and protective clothing.
  • Minimize dust generation during handling.
  • Wash thoroughly after handling.

Storage

  • Store in a cool, dry, and well-ventilated place.
  • Keep containers tightly closed and sealed, protected from moisture and direct sunlight.
  • Store away from incompatible materials (e.g., strong oxidizing agents, strong bases).
  • Recommended storage temperature: Room temperature, in a cool and dark place.
  • Ensure containers are clearly labeled.

Safety & Regulations

This section provides essential safety and regulatory information for **Para Anisic Acid, CAS No. 100-09-4**. It is crucial to handle this chemical with appropriate precautions and in accordance with all applicable local, national, and international regulations.

Product Identification

Product Name: Para Anisic Acid
Synonym: 4-Methoxy Benzoic Acid
CAS Number: 100-09-4
Molecular Formula: C8H8O3

GHS Classification

This product is classified according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).

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WARNING

Hazard Statements (H-codes):

  • H302: Harmful if swallowed.
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
  • H335: May cause respiratory irritation.

Precautionary Statements (P-codes):

  • P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264: Wash skin thoroughly after handling.
  • P270: Do not eat, drink or smoke when using this product.
  • P271: Use only outdoors or in a well-ventilated area.
  • P280: Wear protective gloves/eye protection/face protection.
  • P301+P312+P330: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
  • P302+P352: IF ON SKIN: Wash with plenty of soap and water.
  • P304+P340+P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P332+P313: If skin irritation occurs: Get medical advice/attention.
  • P337+P313: If eye irritation persists: Get medical advice/attention.
  • P362: Take off contaminated clothing and wash before reuse.
  • P403+P233: Store in a well-ventilated place. Keep container tightly closed.
  • P405: Store locked up.
  • P501: Dispose of contents/container to an approved waste disposal plant.

Transport Information

UN Number: Not Regulated
Proper Shipping Name: Not Applicable
Hazard Class: Not Applicable
Packing Group: Not Applicable
Scale
Commercial
Supply Ability
120MT/Annum
Quality/Grade
Pharma/ Cosmetics

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