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2-METHYL-5-NITROANILINE CAS NO. 99-55-8 - Chemical Analysis Dashboard

2-METHYL-5-NITROANILINE

CAS NO. 99-55-8 | Fast Scarlet G Base

General Information

Chemical Structure

2-Methyl-5-Nitroaniline Chemical Structure

Basic Details

CAS Number: 99-55-8
Molecular Formula: C₇H₈N₂O₂
Molecular Weight: 152.15 g/mol
Appearance: Golden yellow powder

Physical Properties

Melting Point: 100–107°C
Solubility: Soluble in alcohol, ether
Density: 1.33 g/cm³
Boiling Point: 305°C

Applications & Grade

2-Methyl-5-Nitroaniline is a crucial intermediate in the synthesis of Imatinib Mesylate, a first-line medication used in the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GIST). Its chemical structure supports the development of kinase inhibitors in targeted cancer therapies.

Also known as Fast Scarlet G Base, this compound plays a vital role in the production of azo pigments such as Pigment Red 17 and Pigment Red 22, widely used in textile, plastic, and ink industries for their high color strength and stability.

  • Production of Azo Dyes
  • Coloring textiles, leather, and paper
  • Pigment synthesis for paints and plastics

It is employed in the synthesis of organic intermediates, including Indazole derivatives, as well as in agrochemicals, photographic chemicals, and other fine chemical formulations, where selective nitration and amine functionalities are essential.

2-Methyl-5-Nitroaniline is used as a hair dye intermediate, particularly in the synthesis of 2-Methyl-5-Nitrophenol, a compound used in oxidative hair dye formulations. It provides vibrant color deposition and is typically used under controlled conditions in professional-grade products.

Product Specifications

Property Value
CAS Number 99-55-8
Chemical Formula C7H8N2O2
Molecular Weight 152.15 g/mol
Appearance Golden yellow powder
Purity ≥ 98% (Pharma/Cosmetic grade available)
Melting Point 100–107°C
Impurity Profile Available upon specific request

Certificate of Analysis

Certificate of Analysis
Product Name: Fast Scarlet G Base
(2-Methyl-5-Nitroaniline)
Mol. Wt.: 152.15 g/mol
Lot Nos.: 116/127/25
CAS No.: 99-55-8
Mfg Date: Jan 2025
Quantity: 1175 kg on dry basis
1632.310 kg on wet basis
Re-Test Date: Jan 2027
A.R. No.: FTR/24-25/012/45
Date of Analysis: Jan 12, 2025

Physical Appearance

Specification: Golden Yellow Powder

Results: Golden Yellow Powder

Purity

Specification: 98% Min. by HPLC

Results: 99.1% By HPLC

Melting Point

Specification: 100-107°C

Results: 105°C

Moisture Content

Specification: NMT 0.5%

Results: 0.2%

Isomer Content

Specification: Not Detected

Results: Not Detected

Conclusion: Material complies with above mentioned specifications
12.01.2025
Analysed By:
V.M.Patel (QC Chemist)
Checked By:
N.M. Shah (QC Manager)
Approved By:
V.Prasad(Technical Head)

HPLC Chromatogram Analysis

Chromatogram

Peak Distribution

Peak Table

Peak Retention Time (min) Area Height Area % Rel. RT

Analysis Summary

The chromatogram shows a main peak at 19.585 minutes with 99.986% purity, indicating high sample purity. Two minor impurity peaks were detected at 3.641 min (0.013%) and 4.546 min (0.001%).

Sample Information

Raw Data (JS / CSV / Python)

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Packaging, Handling & Storage

Packaging

  • 25 kg fiber drums with inner plastic liner
  • 50 kg fiber drums with inner plastic liner
  • Custom packaging options available upon request
  • Designed for moisture barrier protection
  • Robust and secure for transport

Handling

  • Wear appropriate personal protective equipment (PPE)
  • Ensure adequate ventilation during handling
  • Avoid dust formation and inhalation
  • Use non-sparking tools to prevent ignition
  • Follow all local and national safety protocols

Storage

  • Store in a cool, dry, and well-ventilated area
  • Keep container tightly closed when not in use
  • Protect from direct sunlight and heat sources
  • Recommended storage temperature: 15-25°C
  • Shelf life: 2 years from manufacturing date under proper conditions

Safety & Regulations

This section provides essential safety and regulatory information for **Fast Scarlet G Base (2-Methyl-5-Nitroaniline), CAS No. 99-55-8**. It is crucial to handle this chemical with appropriate precautions and in accordance with all applicable local, national, and international regulations.

Product Identification

Product Name: Fast Scarlet G Base
Chemical Name: 2-Methyl-5-Nitroaniline
CAS Number: 99-55-8
Molecular Formula: C7H8N2O2

GHS Classification

This product is classified according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).

Toxic Pictogram

Toxic

Health Hazard Pictogram

Health Hazard

Environmental Hazard Pictogram

Environmental Hazard

DANGER

Transport Information

UN Number: UN2660
Proper Shipping Name: NITROANILINES, SOLID, TOXIC
Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Shipping Name (IATA): NITROANILINES, SOLID, TOXIC
Shipping Name (IMO): NITROANILINES, SOLID, TOXIC
Shipping Name (RID/ADR): NITROANILINES, SOLID, TOXIC
Scale
Commercial
Supply Ability
150MT/Annum
Quality
Pharma/Cosmetics

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