2-METHYL-5-NITROPHENOL
General Information
Chemical Structure
Basic Details
Physical Properties
Applications & Grade
2-Methyl-5-Nitrophenol is a specialty intermediate primarily used in the synthesis of other key components for permanent hair coloring formulations.
- It serves as a crucial precursor for the production of 2-Methyl-5-aminophenol (also known as 5-Amino-2-methylphenol or 4-Amino-2-hydroxytoluene).
- 2-Methyl-5-aminophenol is a widely used secondary intermediate (coupler) in oxidative hair dyes. It reacts with primary intermediates and hydrogen peroxide inside the hair shaft to form larger, colored molecules that become trapped, providing long-lasting color.
- This process allows for a wide range of permanent hair colors, offering excellent gray coverage and color durability.
Our 2-Methyl-5-Nitrophenol is available in a specialized grade suitable for its intended application.
- **Cosmetics Grade:** Produced and tested to meet the high purity and quality standards required for use as an intermediate in cosmetic products, specifically hair dyes.
Product Specifications
| Tests | Specification |
|---|---|
| Appearance | Pale beige powder |
| Melting point | 111 – 115°C |
| Moisture content | < 0.2% |
| Loss on drying @ 80°C for 4 hrs | < 0.2% |
| Solubility | Soluble in methanol. Insoluble in water. |
| Sulphated ash | < 0.3% |
| Purity by Chromatography | > 99.0% |
Certificate of Analysis
(2M5NP)
Appearance
Specification: Pale beige powder
Result: Pale beige powder
Melting point
Specification: 111 – 115°C
Result: 111 – 115°C
Moisture content
Specification: < 0.2%
Result: < 0.2%
Loss on drying @ 80°C for 4 hrs
Specification: < 0.2%
Result: < 0.2%
Solubility
Specification: Soluble in methanol. Insoluble in water.
Result: Soluble in methanol. Insoluble in water.
Sulphated ash
Specification: < 0.3%
Result: < 0.3%
Purity by Chromatography
Specification: > 99.0%
Result: 99.25 %
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QC Manager
Technical Head
Spectroscopic Analysis
HPLC Chromatogram Coming Soon!
We are currently preparing the interactive HPLC data for 2-Methyl-5-Nitrophenol.
Please check back later for detailed chromatographic analysis.
Packaging, Handling & Storage
Packaging
- Typically supplied in sealed, moisture-proof containers such as fiber drums with inner PE liners, or bags.
- Available in various sizes (e.g., 25kg, 50kg, 500kg) to meet specific customer requirements.
- Containers are designed to protect the product from moisture and contamination.
Handling
- Handle in a well-ventilated area or under local exhaust ventilation to prevent dust inhalation.
- Avoid direct contact with skin, eyes, and clothing.
- Wear appropriate personal protective equipment (PPE): chemical-resistant gloves, safety goggles/face shield, and protective clothing.
- Minimize dust generation and accumulation during handling.
- Wash thoroughly after handling.
Storage
- Store in a cool, dry, and well-ventilated place.
- Keep containers tightly closed and sealed, protected from moisture and direct sunlight.
- Store away from incompatible materials (e.g., strong oxidizing agents, strong bases).
- Recommended storage temperature: Room temperature.
- Ensure containers are clearly labeled.
Safety & Regulations
This section provides essential safety and regulatory information for **2-Methyl-5-Nitrophenol, CAS No. 5428-54-6**. It is crucial to handle this chemical with appropriate precautions and in accordance with all applicable local, national, and international regulations.
Product Identification
GHS Classification
This product is classified according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).
Exclamation Mark
Skull and Crossbones
Hazard Statements (H-codes):
- H302: Harmful if swallowed.
- H311: Toxic in contact with skin.
- H315: Causes skin irritation.
- H319: Causes serious eye irritation.
- H332: Harmful if inhaled.
- H335: May cause respiratory irritation.
Precautionary Statements (P-codes):
- P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
- P262: Do not get in eyes, on skin, or on clothing.
- P264: Wash skin thoroughly after handling.
- P270: Do not eat, drink or smoke when using this product.
- P271: Use only outdoors or in a well-ventilated area.
- P280: Wear protective gloves/eye protection/face protection.
- P301+P317: IF SWALLOWED: Call a POISON CENTER/doctor.
- P302+P352: IF ON SKIN: Wash with plenty of water.
- P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P316: Get emergency medical help immediately.
- P317: Get medical help/attention.
- P319: Get immediate medical help/attention.
- P321: Specific treatment (see supplemental first aid instructions on this label).
- P330: Rinse mouth.
- P332+P317: If skin irritation occurs: Get medical advice/attention.
- P337+P317: If eye irritation persists: Get medical advice/attention.
- P361+P364: Take off immediately all contaminated clothing and wash it before reuse.
- P362+P364: Take off contaminated clothing and wash it before reuse.
- P403+P233: Store in a well-ventilated place. Keep container tightly closed.
- P405: Store locked up.
- P501: Dispose of contents/container to an approved waste disposal plant.
Transport Information
Downloads
Safety Data Sheet (SDS)
Comprehensive safety information for handling and storage of 2-Methyl-5-Nitrophenol.
Certificate of Analysis (COA)
Batch-specific analytical results and quality assurance for 2-Methyl-5-Nitrophenol.
Technical Data Sheet (TDS)
Detailed product specifications and typical properties for 2-Methyl-5-Nitrophenol.
HPLC Analytical Report
Full HPLC chromatogram and peak analysis report (Coming Soon).