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2-METHYL-4-NITROANILINE CAS NO. 99-52-5 - Chemical Analysis Dashboard

2-METHYL-4-NITROANILINE

CAS NO. 99-52-5 | Fast Red RL Base

General Information

Chemical Structure

2-Methyl-4-Nitroaniline Chemical Structure

Basic Details

CAS Number: 99-52-5
Molecular Formula: C₇H₈N₂O₂
Molecular Weight: 152.15 g/mol
Appearance: Greenish Yellow crystalline powder

Physical Properties

Melting Point: 118-120°C
Solubility: Soluble in alcohol, ether
Density: 1.33 g/cm³
Boiling Point: 305°C

Applications & Grade

2-Methyl-4-Nitroaniline is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly in the production of certain analgesics and anti-inflammatory drugs. Its specific chemical properties make it valuable for building complex molecular structures in medicinal chemistry.

  • Synthesis of Active Pharmaceutical Ingredients (APIs)
  • Precursor for analgesic and anti-inflammatory drugs
  • Research and development in drug discovery

This compound is widely known as Fast Red RL Base due to its extensive use in the dye industry. It serves as a crucial intermediate for synthesizing azo dyes, which are used for coloring textiles, leather, paper, and plastics, providing vibrant red and orange shades.

  • Production of Azo Dyes (e.g., Fast Red RL)
  • Coloring textiles, leather, and paper
  • Pigment synthesis for paints and plastics

Beyond its primary applications, 2-Methyl-4-Nitroaniline finds use in the broader specialty and fine chemical sector. It is employed in the production of various organic intermediates, agrochemicals, and photographic chemicals where its specific reactivity is required.

  • Synthesis of organic intermediates
  • Component in agrochemical formulations
  • Used in photographic chemicals

In the cosmetics and personal care industry, derivatives of 2-Methyl-4-Nitroaniline can be used as colorants in hair dyes and other cosmetic formulations, adhering to strict regulatory standards for safety and purity.

  • Hair dye formulations
  • Other cosmetic colorants (with careful regulation)
  • Ingredient in certain personal care products

Product Specifications

Property Value
Appearance Bright Greenish Yellow Powder
Purity by HPLC 99.5%
Moisture Content Available on dry (moisture NMT 0.5%) and wet basis
Melting Point on dry basis 129-130 °C
Isomer O.T. content NIL by HPLC
Impurity Profile Available upon specific request

Certificate of Analysis

Certificate of Analysis
Product Name: Fast Red RL Base
(2-Methyl-4-Nitroaniline)
Mol. Wt.: 152.15 g/mol
Lot Nos.: 116/127/25
CAS No.: 99-52-5
Mfg Date: Jan 2025
Quantity: 1175 kg on dry basis
1632.310 kg on wet basis
Re-Test Date: Jan 2027
A.R. No.: FTR/24-25/012/45
Date of Analysis: Jan 12, 2025

Physical Appearance

Specification: Bright Greenish Yellow Moist Powder

Results: Bright Greenish Yellow Moist Powder

Purity

Specification: 65 %. By N.V.
99.0% Min. by HPLC

Results: 72.0 %. By N.V.
99.93 % By HPLC

Diazo

Specification: Absolute Clear

Results: Absolute Clear

Isomer (O.T.Cont)

Specification: Nil (By HPLC)
Di Nitro O.T. < 0.1 %

Results: Nil (By HPLC)
Di Nitro O.T. < 0.05 %

Melting Point (on dry basis)

Specification: 129-130°C

Results: 129-130°C

Conclusion: Material complies with above mentioned specifications
12.01.2025
Analysed By:
V.M.Patel (QC Chemist)
Checked By:
N.M. Shah (QC Manager)
Approved By:
V.Prasad(Technical Head)

HPLC Chromatogram Analysis

Chromatogram

Peak Distribution

Peak Table

Peak Retention Time (min) Area Height Area % Rel. RT

Analysis Summary

The chromatogram shows a main peak at 19.585 minutes with 99.986% purity, indicating high sample purity. Two minor impurity peaks were detected at 3.641 min (0.013%) and 4.546 min (0.001%).

Sample Information

Raw Data (JS / CSV / Python)

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Packaging, Handling & Storage

Packaging

  • 25 kg fiber drums with inner plastic liner
  • 50 kg fiber drums with inner plastic liner
  • Custom packaging options available upon request
  • Designed for moisture barrier protection
  • Robust and secure for transport

Handling

  • Wear appropriate personal protective equipment (PPE)
  • Ensure adequate ventilation during handling
  • Avoid dust formation and inhalation
  • Use non-sparking tools to prevent ignition
  • Follow all local and national safety protocols

Storage

  • Store in a cool, dry, and well-ventilated area
  • Keep container tightly closed when not in use
  • Protect from direct sunlight and heat sources
  • Recommended storage temperature: 15-25°C
  • Shelf life: 2 years from manufacturing date under proper conditions

Safety & Regulations

This section provides essential safety and regulatory information for **Fast Red RL Base (2-Methyl-4-Nitroaniline), CAS No. 99-52-5**. It is crucial to handle this chemical with appropriate precautions and in accordance with all applicable local, national, and international regulations.

Product Identification

Product Name: Fast Red RL Base
Chemical Name: 2-Methyl-4-Nitroaniline
CAS Number: 99-52-5
Molecular Formula: C7H8N2O2

GHS Classification

This product is classified according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).

Toxic Pictogram

Toxic

Health Hazard Pictogram

Health Hazard

Environmental Hazard Pictogram

Environmental Hazard

DANGER

Transport Information

UN Number: UN2660
Proper Shipping Name: NITROANILINES, SOLID, TOXIC
Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Shipping Name (IATA): NITROANILINES, SOLID, TOXIC
Shipping Name (IMO): NITROANILINES, SOLID, TOXIC
Shipping Name (RID/ADR): NITROANILINES, SOLID, TOXIC
2-METHYL-4-NITROANILINE CAS NO. 99-52-5
Scale
Commercial
Supply Ability
150MT/Annum
Quality
Pharma/Cosmetics

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