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1-INDANONE

CAS NO. 83-33-0 | α-Hydrindone

General Information

Chemical Structure

1-Indanone Chemical Structure

Basic Details

CAS Number: 83-33-0
Molecular Formula: C₉H₈O
Molecular Weight: 132.16 g/mol
Appearance: Yellowish to white Crystalline

Physical Properties

Melting Point: 38°C to 40°C
Solubility: Soluble in MDC (Dichloromethane)
Density: 1.099 g/cm³
Boiling Point: 243-245°C

Applications & Grade

1-Indanone is a critical building block for several key Active Pharmaceutical Ingredients (APIs). Its indane structure is a core component in various modern drugs.

  • **Indinavir:** Used as an intermediate in the synthesis of Indinavir, an HIV protease inhibitor.
  • **Rasagiline Mesylate:** A key starting material for Rasagiline, a medication used to treat Parkinson's disease.
  • **1-Aminoindane:** Serves as a precursor to 1-aminoindane, which is a building block for various other pharmaceutical agents.

Used in organic synthesis for creating complex indane derivatives used in agrochemicals, fragrances, and material science.

Product Specifications

Property Value
Appearance Yellowish to white Crystalline
Solubility Soluble in MDC
Melting Point 38°C to 40°C
Purity by GC NLT 99.0%

Certificate of Analysis

Certificate of Analysis
Product Name: 1-INDANONE
Mol. Wt.: 132.16 g/mol
Batch No.: IND/002/24
CAS No.: 83-33-0
Mfg Date: Jan-2024
Quantity: 100 kg
Retest Date: Jan-2025
A.R. No.: FP/21/016
Date of Analysis: 12-01-2024

1. Appearance

Specification: Yellowish to white Crystalline

Results: Complies

2. Solubility

Specification: Soluble in MDC

Results: Soluble

3. Melting Point

Specification: 38°C to 40°C

Results: 38°C to 40°C

4. Purity by GC

Specification: NLT 99.0%

Results: 99.261%

Conclusion: The product complies as per above specifications.
12.01.2024
Analysed By:
Nakan
Nilesh Badgujar Signature
Checked By:
Nilesh Badgujar (Quality Control Executive)
Approved By:
(QC Manager)

HPLC Chromatogram Analysis

HPLC Chromatogram (Detector A 210nm)

Peak Distribution

Peak Table

Peak# Retention Time (min) Area Area % Height Height %

Analysis Summary

The HPLC chromatogram confirms the high purity of the 1-Indanone sample. The main peak is observed at **17.258 minutes** [cite: 596], accounting for **99.675%** of the total area[cite: 596]. All other detected impurities are minor, resulting in a product that meets high-purity standards.

Sample Information

Raw Data (JS / CSV / Python)

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Packaging, Handling & Storage

Packaging

  • 25 kg fiber drums
  • 50 kg fiber drums
  • Custom packaging options available upon request
  • Packaged in light-resistant containers

Handling

  • Wear appropriate personal protective equipment (PPE): gloves, safety goggles, lab coat.
  • Ensure adequate ventilation during handling.
  • Avoid dust formation and inhalation.
  • Avoid contact with skin, eyes, and clothing.
  • Wash hands thoroughly after handling.

Storage

  • Store in a cool, dry, and well-ventilated area.
  • Keep container tightly closed when not in use.
  • Protect from direct sunlight and heat sources.
  • Recommended storage temperature: 15-25°C.

Safety & Regulations

This section provides essential safety and regulatory information for **1-Indanone, CAS No. 83-33-0**. It is crucial to handle this chemical with appropriate precautions.

Product Identification

Product Name: 1-Indanone
Synonym: α-Hydrindone
CAS Number: 83-33-0
Molecular Formula: C₉H₈O

GHS Classification

This product is classified according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS).

Exclamation Mark Pictogram

Harmful / Irritant

WARNING

Hazard Statements

  • **H302:** Harmful if swallowed.
  • **H315:** Causes skin irritation.
  • **H319:** Causes serious eye irritation.
  • **H335:** May cause respiratory irritation.

Transport Information

UN Number: Not regulated
Proper Shipping Name: Not classified as a dangerous good for transport.
Hazard Class: N/A
Packing Group: N/A
Scale
Commercial
Supply Ability
100MT/Annum
Quality
Pharma/Speciality

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